Fig. 2
From: Biomarker and genomic analyses reveal molecular signatures of non-cardioembolic ischemic stroke
Clustering analysis reveals subpopulations associated with clinical phenotypes and outcomes of non-cardioembolic ischemic stroke (NCIS). a A heatmap illustrating 30 clusters based on 63 circulating biomarkers. b Characterization of clinical phenotypes and medication use across clusters. c Cumulative risk of stroke recurrence at 1 year for the 30 clusters. d Cumulative risk of mortality at 1 year for the 30 clusters. e Cumulative risk of poor functional outcome at 3 months for the 30 clusters. f Kaplan–Meier curves of time to stroke recurrence within 1-year post-stroke for the 30 clusters. g Uniform manifold approximation and projection (UMAP) of 30 molecular clusters. h t-distributed stochastic neighbor embedding (t-SNE) of 30 molecular clusters. i Incidence of poor functional outcome in patients with or without aspirin therapy (*P < 0.05). j Incidence of stroke recurrence in patients with or without aspirin therapy (*P < 0.05)
