Table 2 Differential metabolites responsible for the discrimination of two groups
From: Urinary biomarker panel for diagnosing patients with depression and anxiety disorders
Metabolite | P valuea | Rb | FCc | Metabolic pathway |
|---|---|---|---|---|
N-methylnicotinamide | 5.32E−06 | −0.693 | −1.93337 | Tryptophan–nicotinic acid metabolism |
Acetone | 0.008495 | −0.501 | −0.61032 | Propanoate metabolism |
(S)−3,4-dihydroxybutyric acid | 0.002106 | 0.714 | 0.27378 | Not found |
(S)−3-hydroxyisobutyric acid | 0.265085 | 0.523 | 0.841019 | Valine, leucine and isoleucine degradation |
Adipic acid | 0.737113 | 0.46 | 0.347352 | Degradation of aromatic compounds |
l-alanine | 0.096207 | 0.535 | 0.411909 | Alanine metabolism |
Aminomalonic acid | 0.001461 | 0.77 | 1.070629 | Not found |
Azelaic acid | 3.86E−05 | 0.662 | 1.841785 | Lipid metabolism |
Citric acid | 0.088148 | 0.527 | 0.367736 | Citrate cycle (TCA cycle) |
Fructose | 0.006761 | 0.525 | 0.66192 | Starch and sucrose metabolism |
Glycine | 0.001052 | 0.654 | 0.561433 | Glycine, serine and threonine metabolism |
Hippuric acid | 0.001068 | −0.858 | −1.02191 | Tyrosine–phenylalanine pathway |
Indican | 5.62E−05 | −0.8 | −0.92295 | Not found |
l-lactic acid | 0.001359 | 0.487 | 0.632744 | Propanoate metabolism |
Methylmalonic acid | 0.007244 | −0.671 | −0.63621 | Propanoate metabolism |
Pseudouridine | 9.33E−05 | −0.477 | −0.64546 | Pyrimidine metabolism |
Ribose | 0.347268 | 0.612 | 0.214255 | Pentose phosphate pathway |
Sorbitol | 0.113869 | 0.449 | 0.651624 | Galactose metabolism |
l-threonine | 0.012509 | 0.505 | 0.330823 | Glycine, serine and threonine metabolism |
α-Aminobutyric acid | 0.036643 | 0.486 | 0.217817 | Cysteine and methionine metabolism |
