Fig. 2

River plots showing the progress of women’s risk classification for years 4–1 tDx by taking the risk classification of the latest sample available prior to each annual screen cut-off. Plots based on the novel panel for Type I EOC cases (not used to train model) Type II EOC cases (used to train model) and controls may be compared. Risk classification elevates through intermediate (I), elevated (E) and severe (S) for the novel panel for both Type I and Type II cases whereas the majority of control women remain classified as normal. Coloured lines indicate risk classifications, normal (N) is green, intermediate (I) yellow, elevated (E) orange and severe (S) red