Fig. 2: The expression pattern of WDR1 in pancreatic cancer. | British Journal of Cancer

Fig. 2: The expression pattern of WDR1 in pancreatic cancer.

From: WD repeat-containing protein 1 maintains β-Catenin activity to promote pancreatic cancer aggressiveness

Fig. 2

a Combined data from TCGA dataset and GTEx portal (http://gemini.cancer-pku.cn/) showed that the mRNA expression level of WDR1 in pancreatic cancer (n = 179) was significantly higher than that in normal pancreas tissues (n = 175). b Western blotting shows the protein expression levels of WDR1 in normal pancreas and pancreatic cancer with different TNM stages. c Quantitative analysis of the expression levels (relative band density) of WDR1 in normal pancreas (N), and pancreatic cancer with different TNM stages (IIA, IIB, III and IV). d Representative images of WDR1 staining in normal pancreas and PDAC tissues with increasing TNM stages. e The frequency distribution of WDR1 expression in low-stage PDAC tissues (n = 40), high-stage PDAC tissues (n = 41) and normal pancreas tissues (n = 44). f Kaplan–Meier analysis of the overall survival of PDAC patients based on the protein expression of WDR1. *P < 0.05, **P < 0.01, ***P < 0.001.

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