Table 1 Participant characteristics by age-adjusted and sex-specific cardiorespiratory fitness (VO2max per kg total-body mass) tertiles.

From: Observational and genetic associations between cardiorespiratory fitness and cancer: a UK Biobank and international consortia study

  

Women

  

Men

 

Lower fitness

Mid fitness

Higher fitness

Lower fitness

Mid fitness

Higher fitness

N

12,791

12,790

12,786

11,404

11,402

11,399

Age (y)

57 ± 8

57 ± 8

57 ± 8

58 ± 8

58 ± 8

58 ± 8

Height (m)

1.63 ± 0.06

1.63 ± 0.06

1.63 ± 0.06

1.76 ± 0.07

1.76 ± 0.07

1.76 ± 0.07

Total body mass (kg)

79.6 ± 14.8

69.5 ± 10.0

62.6 ± 8.2

94.4 ± 14.2

84.6 ± 10.6

77.3 ± 9.8

Fat-free mass (kg)

46.5 ± 5.4

44.0 ± 4.2

42.6 ± 3.9

66.9 ± 7.8

63.2 ± 6.9

60.6 ± 6.5

BMI (kgm−2)

30.1 ± 5.3

26.2 ± 3.5

23.5 ± 2.8

30.3 ± 4.1

27.3 ± 2.9

25.1 ± 2.7

VO2maxtbm(mlmin−1kg−1)

19.7 ± 3.2

25.1 ± 1.9

31.4 ± 4.7

26.0 ± 2.9

31.7 ± 2.0

38.4 ± 4.2

VO2maxffm (mlmin−1kg−1)

33.4 ± 5.8

39.5 ± 3.8

45.8 ± 6.2

36.5 ± 4.0

42.4 ± 3.1

48.8 ± 4.8

Red meat consumption

0.8 ± 0.5

0.8 ± 0.5

0.7 ± 0.5

1.1 ± 0.6

1.0 ± 0.6

0.9 ± 0.6

Fish consumption

  Never

10.7% (1363)

9.1% (1161)

8.3% (1060)

11.8% (1343)

11.1% (1265)

8.8% (1006)

  At most 1 per week

33.0% (4226)

32.2% (4114)

31.4% (4013)

36.4% (4148)

33.9% (3868)

32.3% (3687)

  2 or more per week

55.6% (7116)

58.1% (7431)

60.0% (7674)

50.8% (5794)

54.4% (6202)

58.3% (6646)

  Missing

0.7% (86)

0.7% (84)

0.3% (39)

1.0% (119)

0.6% (67)

0.5% (60)

Fruit & vegetable consumption

  Never

17.4% (2232)

15.4% (1974)

12.8% (1639)

24.9% (2834)

23.8% (2713)

19.3% (2199)

  At most 1 per week

29.0% (3707)

28.5% (3643)

26.2% (3355)

33.5% (3816)

32.1% (3663)

31.8% (3626)

  2 or more per week

53.2% (6804)

55.9% (7144)

60.8% (7772)

41.2% (4697)

43.8% (4998)

48.7% (5549)

  Missing

0.4% (48)

0.2% (29)

0.2% (20)

0.5% (57)

0.2% (28)

0.2% (25)

Salt addition to meals

  Never/rarely

58.0% (7418)

58.3% (7455)

59.0% (7547)

52.8% (6022)

56.1% (6395)

60.2% (6864)

  Sometimes

26.9% (3443)

27.4% (3510)

27.3% (3489)

29.3% (3343)

27.9% (3186)

25.7% (2930)

  Usually/always

14.8% (1892)

14.1% (1800)

13.6% (1733)

17.5% (1994)

15.8% (1806)

13.9% (1588)

  Missing

0.3% (38)

0.2% (25)

0.1% (17)

0.4% (45)

0.1% (15)

0.1% (17)

Alcohol consumption

  Never or previous

11.3% (1439)

8.2% (1055)

6.4% (812)

6.9% (785)

5.7% (648)

5.3% (599)

  At most 2 per week

59.5% (7615)

52.8% (6755)

47.1% (6021)

46.4% (5286)

41.6% (4743)

39.0% (4442)

  3 or more per week

28.9% (3697)

38.7% (4947)

46.4% (5930)

46.3% (5282)

52.5% (5990)

55.6% (6340)

  Missing

0.3% (40)

0.3% (33)

0.2% (23)

0.4% (51)

0.2% (21)

0.2% (18)

Smoking status

  Never

63.7% (8147)

61.5% (7869)

59.7% (7635)

48.3% (5511)

51.5% (5869)

55.5% (6326)

  Previous

29.0% (3704)

31.2% (3987)

32.6% (4173)

40.6% (4625)

38.2% (4357)

34.4% (3917)

  Current

6.7% (858)

6.9% (879)

7.3% (932)

10.3% (1180)

9.8% (1121)

9.7% (1105)

  Missing

0.6% (82)

0.4% (55)

0.4% (46)

0.8% (88)

0.5% (55)

0.4% (51)

Townsend deprivation index

−1.0 ± 3.0

−1.4 ± 2.8

−1.5 ± 2.8

−1.0 ± 3.1

−1.4 ± 2.9

−1.5 ± 2.9

Education

  No qualification

14.4% (1841)

11.0% (1413)

8.3% (1059)

14.8% (1684)

12.1% (1378)

9.4% (1072)

  Any other qualification

53.8% (6885)

51.4% (6577)

46.3% (5925)

52.0% (5929)

48.9% (5579)

42.6% (4857)

  Degree level or above

30.4% (3887)

36.6% (4678)

44.8% (5724)

31.7% (3618)

38.0% (4336)

47.3% (5391)

  Missing

1.4% (178)

1.0% (122)

0.6% (78)

1.5% (173)

1.0% (109)

0.7% (79)

Employment

  Unemployed

9.9% (1265)

7.9% (1011)

8.3% (1061)

7.9% (903)

5.7% (651)

4.9% (557)

  Employed

52.8% (6752)

55.9% (7147)

57.5% (7355)

56.7% (6467)

60.3% (6873)

61.3% (6992)

  Retired

36.6% (4684)

35.7% (4572)

33.8% (4320)

34.5% (3939)

33.4% (3813)

33.3% (3794)

  Missing

0.7% (90)

0.5% (60)

0.4% (50)

0.8% (95)

0.6% (65)

0.5% (56)

Race

  Asian or Asian British

3.3% (425)

2.4% (303)

1.6% (201)

3.5% (400)

3.6% (413)

2.4% (269)

  Black or Black British

5.2% (670)

2.2% (281)

0.9% (117)

3.5% (398)

2.2% (254)

1.2% (138)

  Mixed

1.0% (126)

0.9% (112)

0.9% (117)

0.7% (78)

0.7% (75)

0.7% (80)

  Other

1.9% (243)

1.9% (240)

1.8% (234)

1.6% (180)

1.5% (174)

1.6% (180)

  White

87.8% (11,235)

92.1% (11784)

94.3% (12,062)

89.9% (10,251)

91.3% (10,415)

93.6% (10,673)

 Missing

0.7% (92)

0.5% (70)

0.4% (55)

0.9% (97)

0.6% (71)

0.5% (59)

Hypertension

  Not hypertensive

39.9% (5109)

56.2% (7193)

67.6% (8647)

26.2% (2987)

41.3% (4707)

55.4% (6316)

  Hypertensive

60.1% (7682)

43.8% (5597)

32.4% (4139)

73.8% (8417)

58.7% (6695)

44.6% (5083)

Diabetes

  Not diabetic

93.3% (11,940)

97.3% (12,446)

98.6% (12,603)

87.5% (9980)

94.7% (10,801)

97.1% (11,067)

  Diabetic

6.3% (805)

2.5% (316)

1.3% (167)

12.1% (1376)

5.1% (586)

2.8% (316)

  Missing

0.4% (46)

0.2% (28)

0.1% (16)

0.4% (48)

0.1% (15)

0.1% (16)

Colorectal cancer

1.0% (133)

0.9% (112)

0.8% (98)

1.5% (169)

1.5% (173)

1.1% (126)

  Colon

0.8% (103)

0.7% (93)

0.6% (74)

1.0% (119)

1.1% (122)

0.8% (87)

  Rectal

0.4% (45)

0.3% (35)

0.3% (41)

0.7% (85)

0.7% (78)

0.6% (64)

Lung cancer

0.6% (77)

0.6% (71)

0.6% (82)

0.9% (103)

0.7% (76)

0.6% (71)

Breast cancer

3.2% (410)

2.8% (352)

2.6% (331)

   

Endometrial cancer

0.7% (93)

0.4% (54)

0.3% (37)

   

Ovarian cancer

0.3% (44)

0.3% (36)

0.4% (56)

   

Prostate cancer

   

4.2% (481)

5.1% (579)

4.6% (526)