Fig. 2: Hsa_circ_0013561 downregulation inhibits OC cell proliferation and tumor growth. | Cancer Gene Therapy

Fig. 2: Hsa_circ_0013561 downregulation inhibits OC cell proliferation and tumor growth.

From: Hsa_circ_0013561 promotes epithelial-mesenchymal transition and tumor progression by regulating ANXA2 via miR-23b-3p in ovarian cancer

Fig. 2

A The expression of hsa_circ_0013561 in SKOV3 and A2780 transfected with hsa_circ_0013561 silencing vector (sh-circ-0013561) or control vector (NC), measured by RT-qPCR, ***P < 0.001 vs. NC. B, C The proliferation capacity of SKOV3 and A2780 was detected by CCK8, ***P < 0.001 vs. NC. D, E The proliferation capacity of SKOV3 and A2780, detected by EdU, ***P < 0.001 vs. NC. F Representative photographs of SKOV3 tumor formation in xenograft model of nude mice. G, H Summary of tumor volumes and weights in subcutaneous tumor xenograft model, ***P < 0.001 vs. sh-NC. I, J The relative number of Ki-67 positive cells in subcutaneous xenograft model, measured by immunohistochemical scores, ***P < 0.001 vs. NC.

Back to article page