Fig. 6: Model of Bax/Bak-stimulated autophagy
From: Autophagy induced during apoptosis degrades mitochondria and inhibits type I interferon secretion
Bax/Bak activation induces 3 separate pathways: (1) apoptotic caspase cascade, (2) IFN-β production via the cGAS/STING pathway and (3) autophagy. Both apoptotic caspases and autophagy restrain IFN-β secretion to render apoptotic cells immunologically silent
