Fig. 4: Loss of interaction between RAD51B-c.92delT and RAD51C as well as a reduction of the interaction between RAD51B-c.92delT and HR-specific interactors as revealed by co-immunoprecipitation. | Cell Death & Differentiation

Fig. 4: Loss of interaction between RAD51B-c.92delT and RAD51C as well as a reduction of the interaction between RAD51B-c.92delT and HR-specific interactors as revealed by co-immunoprecipitation.

From: A truncating variant of RAD51B associated with primary ovarian insufficiency provides insights into its meiotic and somatic functions

Fig. 4

HEK293T cells were co-transfected with either RAD51B-WT or RAD51B-c.92delT and A RAD51C-HA, B Flag-RAD51, C HA-HELQ or D Flag-DMC1. Protein complexes were immunoprecipitated with either an anti-RAD51B, anti-Flag, anti-HA or IgGs (negative control), and analyzed by immunoblotting with the indicated antibody. The red > indicates the band corresponding to RAD51B.

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