Fig. 3: hCVPC-extracellular vesicles reduce cell death of cardiomyocyte. | Cell Death & Disease

Fig. 3: hCVPC-extracellular vesicles reduce cell death of cardiomyocyte.

From: Extracellular vesicles from human embryonic stem cell-derived cardiovascular progenitor cells promote cardiac infarct healing through reducing cardiomyocyte death and promoting angiogenesis

Fig. 3

a Representative and quantification of IHC staining for TUNEL+ cells in the border zone of infarcted hearts at day 3 post MI and sham hearts. n = 12 slices from 4 hearts each group. Scale bar, 100 μm. b Cell viability of NRCMs under OGD injury treated with the EV-N and the EV-H, n = 6. Scale bar, 100 μm. c The activity of LDH in the culture medium of NRCMs subjected to a 6-h of OGD injury with and without the treatment of 1 μg EV-N or EV-H. n = 5. *p < 0.05, **p < 0.01, ***p < 0.001. cTnT cardiac troponin T, TUNEL terminal deoxynucleotidyl transferase dUTP nick end labeling, OGD oxygen glucose deprivation.

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