Fig. 2: RNA-seq analysis of the effects of Tfap2c on somatic reprogramming. | Cell Death & Disease

Fig. 2: RNA-seq analysis of the effects of Tfap2c on somatic reprogramming.

From: TFAP2C facilitates somatic cell reprogramming by inhibiting c-Myc-dependent apoptosis and promoting mesenchymal-to-epithelial transition

Fig. 2

a Number of differentially regulated genes after Tfap2c overexpression compared with control on day 4. b Number of differentially regulated genes after Tfap2c overexpression compared with control on day 8. c Venn diagram showing the common genes between Tfap2c-affected genes (day 4) and the previously identified reprogramming genes. Genes that impair (or facilitate) reprogramming and downregulated (or upregulated) simultaneously in our RNA-seq dataset are highlighted in blue (or red). d Venn diagram showing the common genes between Tfap2c-affected genes (day 8) and the previously identified reprogramming genes. e Gene ontology analysis for genes upregulated by Tfap2c on day 4. f Gene ontology analysis for genes upregulated by Tfap2c on day 8.

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