Fig. 1: Overexpression of USP28 is correlated with poor prognosis in PC patients. | Cell Death & Disease

Fig. 1: Overexpression of USP28 is correlated with poor prognosis in PC patients.

From: USP28 facilitates pancreatic cancer progression through activation of Wnt/β-catenin pathway via stabilising FOXM1

Fig. 1

A Representative H&E and IHC staining of USP28 in PC tissues and paired normal tissues (magnification ×100, inset magnification ×400). Scale bar, 50 μm. B qRT-PCR analysis of USP28 mRNA expression in 102 PC tumours and paired normal tissues. **P < 0.01. C, D Determination and quantification of USP28 protein levels in PC tissues and paired normal tissues by western blotting assay. GAPDH was used as a loading control. **P < 0.01. E, F Kaplan–Meier plots representing probabilities of progression-free and overall survival in 102 PC patients according to the expression level of USP28. Statistical analysis was conducted using Student t test and log-rank test.

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