Fig. 2: CircUBE2Q2 promotes the proliferation, migration, and invasion of GC cells in vitro. | Cell Death & Disease

Fig. 2: CircUBE2Q2 promotes the proliferation, migration, and invasion of GC cells in vitro.

From: Circular RNA UBE2Q2 promotes malignant progression of gastric cancer by regulating signal transducer and activator of transcription 3-mediated autophagy and glycolysis

Fig. 2

A Assessment of the proliferation of MKN-45 and BGC-823 cell lines transfected with circUBE2Q2-specific siRNA or an overexpression plasmid by CCK-8 assay. B Assessment of cell proliferation by colony formation assay. C Assessment of cell proliferation by EDU assay. D Assessment of migration and invasion of by transwell assay. E Gastric cancer organoid models indicating the effect of circUBE2Q2 on the growth of GC, scale bar = 25 µm. F The protein level of EMT-related genes (TWIST, Snail, Slug, N-cadherin, and E-cadherin) in GC organoid models detected by western blotting. Data are expressed as the mean ± SD. *p < 0.05, **p < 0.01, ***p < 0.001.

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