Fig. 5: STAT3 reverses the effects of circUBE2Q2 on GC. | Cell Death & Disease

Fig. 5: STAT3 reverses the effects of circUBE2Q2 on GC.

From: Circular RNA UBE2Q2 promotes malignant progression of gastric cancer by regulating signal transducer and activator of transcription 3-mediated autophagy and glycolysis

Fig. 5

A CCK-8 analysis of the cell proliferation ability in MKN-45 and BGC-823 cell lines cotransfected with circUBE2Q2-specific siRNA or STAT3 plasmids. B Colony formation assay of the cell proliferation ability in cotransfected MKN-45 and BGC-823 cell lines. C EdU analysis of the cell proliferation ability in treated MKN-45 and BGC-823 cell lines. D Transwell invasion and migration assay in treated MKN-45 and BGC-823 cell lines. E Western blot analysis of STAT3, p-STAT3, Twist, Snail, and Slug with proteins treated with circUBE2Q2-specific siRNA or STAT3 plasmids in MKN-45 and BGC-823 cell lines. Data are expressed as the mean ± SD. *p < 0.05, **p < 0.01, ***p < 0.001.

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