Fig. 5: ATG3 could be induced by eIF5A2 and HIF-1α.
From: Eukaryotic initiation factor 5A2 mediates hypoxia-induced autophagy and cisplatin resistance
A A scatter plot suggesting that eIF5A2 expression correlated significantly and positively with ATG3 expression (R = 0.36, p < 0.001). B, C Western blotting results demonstrating that ATG3 levels decreased with the knockout of eIF5A2. D qRT-PCR results exhibiting successful transfection. E A scatter plot revealing the significant and positive correlation between HIF-1α and ATG3 expression (R = 0.29, p < 0.001). F–H qRT-PCR (F) and western blotting (G, H) indicating that ATG3 levels decreased after silencing HIF-1α. *P < 0.05, **P < 0.01, ***P < 0.001.
