Fig. 1: LINC00839 is upregulated in GSCs. | Cell Death & Disease

Fig. 1: LINC00839 is upregulated in GSCs.

From: METTL3-mediated m6A modification of LINC00839 maintains glioma stem cells and radiation resistance by activating Wnt/β-catenin signaling

Fig. 1

A Hierarchical clustering of differentially lncRNAs expression in HNP1 and MES28 cells. B LINC00839 expression in NSCs and GSCs was detected by qRT-PCR. C LINC00839 expression in primary (Pri.) and recurrent (Rec.) glioma samples was measured using the CGGA dataset. D LINC00839 expression in U251 cells and GSCs was measured using the GSE124145 dataset. E LINC00839 expression in primary (Pri.) and recurrent (Rec.) GBM samples was detected by qRT-PCR. F, G Glioma samples were divided into two groups: LINC00839 low and high, separated by the median of LINC00839 expression. The correlation between LINC00839 expression and overall survival in glioma patients with or without IR treatment was assessed by Kaplan–Meier survival analysis. H The correlation between LINC00839 expression and overall survival in GBM patients was assessed by Kaplan–Meier survival analysis.

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