Fig. 6: LINC00880 is a promising predictor of poor outcome in early-stage LUAD. | Cell Death & Disease

Fig. 6: LINC00880 is a promising predictor of poor outcome in early-stage LUAD.

From: The super-enhancer-driven lncRNA LINC00880 acts as a scaffold between CDK1 and PRDX1 to sustain the malignance of lung adenocarcinoma

Fig. 6

A Representative image of RNA in situ hybridization (RNA-ISH) of LINC00880 and Immunohistochemistry (IHC) staining sections of patients with LUAD. FOXP3, p-CDK1, p-PRDX1 and p-AKT was significantly high expressed at high LINC00880 expression LUAD patients. Scale bars: 100 μm. B–E FOXP3, p-CDK1 (T161), p-PRDX1 and p-AKT IHC score between low and high LINC00880 expression LUAD patients. F Relative expression of LINC00880 detected by qRT-PCR from different pathological stage of LUAD in our cohort. G, H TCGA-LUAD PFS survival analysis in stage I patients according to the expression of LINC00880 and FOXP3. I Graphic abstract. Figure in I was created using Adobe Illustrator.

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