Fig. 2: Silencing of Plk1 protects against kidney fibrosis in UUO mice.
From: Plk1 promotes renal tubulointerstitial fibrosis by targeting autophagy/lysosome axis
A, B Representative images of HE and Masson staining and immunohistochemistry detection of FN, F4/80 in kidneys of sham and UUO mice with or without Plk1 silencing. Scale bar = 50 µm. C, D Western blot analysis of FN, α-SMA, and Collagen III in kidneys of different groups of mice. E qRT-PCR analysis of FN, α-SMA, and Collagen III in different groups of mice. n = 6. *P < 0.05, **P < 0.01, ***P < 0.001.
