Fig. 6: Kyn level in urine positively correlated with the malignancy of bladder cancer.

The concentration of Kyn in the high-grade group was significantly higher than that in the normal group (a). The concentration of Kyn in the MIBC group was significantly higher than that in the normal group (b). The Kyn levels in urine were positively correlated with tumor size (c) and the percentage of Ki67-positive cells (d). *P < 0.05, **P < 0.01.