Fig. 6: LINC01637 promotes the growth of UM by regulating STAT6. | Cell Death & Disease

Fig. 6: LINC01637 promotes the growth of UM by regulating STAT6.

From: STAT6/LINC01637 axis regulates tumor growth via autophagy and pharmacological targeting STAT6 as a novel strategy for uveal melanoma

Fig. 6

A, B Western blot analysis was performed to examine the expression of STAT6 in the LV-NC group and LV-STAT6 group, which were supplemented with Sh-NC and Sh-LINC01637; (C–F) An investigation was conducted to examine the proliferation, migration, and invasion of two groups: the LV-NC group and the LV-STAT6 group. Both groups were supplemented with Sh-NC or Sh-LINC01637; (G) The volume of tumors formed in the LV-STAT6/Sh-NC group and LV-STAT6/Sh-LINC01637 group; (H) The weight of tumors formed in the LV-STAT6/Sh-NC group and LV-STAT6/Sh-LINC01637 group; (I) Photographs of tumors from the LV-STAT6/Sh-NC group and LV-STAT6/Sh-LINC01637 group. (Scale bar: 100 µm; Data were presented as the mean ± SD; n = 3–6; *p < 0.05, **p < 0.01, ***p < 0.001).

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