Fig. 6: CARM1 enhances the metastatic ability of HCC cells. | Cell Death & Disease

Fig. 6: CARM1 enhances the metastatic ability of HCC cells.

From: PSMD14-mediated deubiquitination of CARM1 facilitates the proliferation and metastasis of hepatocellular carcinoma by inducing the transcriptional activation of FERMT1

Fig. 6

A Representative images of the transwell assay results for control and CARM1-knockdown Huh7 and PLC/PRF/5 cells showing their migration and invasion ability (left). The cells in five randomly selected fields were counted under a microscope, and the data were presented as a bar chart (right). B Representative microscopy images of pulmonary metastatic lesions 8 weeks after the injection of the indicated Huh7 cells into the tail vein of nude mice. C The number of lung metastatic tumors in each group was determined. (n = 3; *p < 0.05, **p < 0.01, and ***p < 0.001).

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