Fig. 2: Overexpression of LUC7L2 promoted radioresistance of NPC cells. | Cell Death Discovery

Fig. 2: Overexpression of LUC7L2 promoted radioresistance of NPC cells.

From: CRISPR/Cas9 genome-wide screening identifies LUC7L2 that promotes radioresistance via autophagy in nasopharyngeal carcinoma cells

Fig. 2

A Comparison of LUC7L2 expression levels in CNE2 and CNE2IR cells. β-actin served as a loading control. B Western blot validation on the establishment of CNE2 cell line with stable LUC7L2 overexpression. β-actin served as a loading control. C Overexpression of LUC7L2 promoted CNE2 radioresistance. LUC7L2 (6 Gy) vs. NEG (6 Gy), n = 5, P < 0.001. D Clonogenic survival analysis on the radioresistance of CNE2 NEG and CNE2 LUC7L2. The colony formation in CNE2 NEG or CNE2 LUC7L2 without IR was regarded as 100%, respectively. LUC7L2 (6 Gy) vs. NEG (6 Gy), n = 3, P < 0.05.

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