Fig. 6: Knockdown of LUC7L2 leads to reduction of SQSTM1 expression.

A Spearman correlation analysis of LUC7L2 and SQSTM1 in HNSCC patients from the TCGA database. B Knockdown of LUC7L2 down-regulates the expression of SQSTM1 in CNE2IR and Hone1IR cells. β-actin served as a loading control. C QPCR analysis of LUC7L2, ATG5, and ATG12 in CNE2IR/Hone1IR shNEG and shLUC7L2 cells.