Fig. 6: In nude mice xenografts, RAD18 promoted tumor progress and M2 polarization. | Cell Death Discovery

Fig. 6: In nude mice xenografts, RAD18 promoted tumor progress and M2 polarization.

From: A positive feedback loop: RAD18-YAP-TGF-β between triple-negative breast cancer and macrophages regulates cancer stemness and progression

Fig. 6

A After 4 weeks, the tumors of nude mice were removed and evaluated by HE staining. Images of dissected xenografted tumors implanted subcutaneously with TNBC cells (shNC/shRAD18 MDA-MB-231 and shNC/shRAD18 HCC-1806) were showed. Tumor growth curves determined by caliper measurements shown as mean (mm3) ± SD. n = 5/group. B H&E and IHC staining of RAD18, YAP, CD44, CD163, and TGFβ in nude mice xenografts tumor samples.

Back to article page