Fig. 2: DHA induces early ferroptosis in AML cells. | Cell Death Discovery

Fig. 2: DHA induces early ferroptosis in AML cells.

From: Dihydroartemisinin-induced ferroptosis in acute myeloid leukemia: links to iron metabolism and metallothionein

Fig. 2

a Viability curves for the indicated cells at 24 h post treatment. Error bars, ± standard deviation (n = 6). b IC50% of DHA treatment for 24 h across the same panel of AML cells based on cell viability (n = 6). c C11-BODIPY staining of MOLM-14 and OCI-AML2 cells treated with increasing with DHA and DHA + Fer-1 Data are expressed in mean fluorescence intensity (MFI) (fold/ DMSO-treated cells) (n = 3). d Apoptosis % (PI staining) of MOLM-14 and OCI-AML2 cells treated with DHA and various cell death inhibitors at 24 h and 48 h (n = 3).

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