Fig. 4: CD1C-CD141- DCs subcluster of critical COVID-19 patients is IFN- unresponsive. | Cell Death Discovery

Fig. 4: CD1C-CD141- DCs subcluster of critical COVID-19 patients is IFN- unresponsive.

From: A burns and COVID-19 shared stress responding gene network deciphers CD1C-CD141- DCs as the key cellular components in septic prognosis

Fig. 4

A UMAP embedding visualization of CD1C-CD141- DC sub-clusters which colored by cluster identity (left) and disease status (right). B Pie chart of CD1C-CD141- DCs composition in each cluster (top) and disease status (bottom), respectively. C Boxplot of SRC genes score among each CD1C-CD141- DC sub-clusters. Cluster1 was compared to the other clusters. D Violin plot of Interferon signaling score across each CD1C-CD141- DC sub-clusters. Kruskal-Wallis test p value was annotated on the top left. UMAP visualization of CD1C-CD141- DC trajectories colored by state (E), pseudotime (F), and disease status (G). H Representative heatmap of differentially expressed and correlated with pseudotime genes.

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