Fig. 2: Upregulation of CAMK2D in BAP1-KO MMe cells.
From: CAMK2D: a novel molecular target for BAP1-deficient malignant mesothelioma
a qRT-PCR analysis of CAMK2D using SYBR Green-based method showing the relative gene expression levels after normalization to GAPDH expression. The relative transcript levels were calculated by comparing the mean values with those from parental cells. Data are expressed as mean ± SE (n = 3). Asterisks indicate significant differences between BAP1-KO#1 and exogenous BAP1/BAP1-KO#1 cells (*p < 0.05). b Western blot analysis for CAMK2D, EZH2, H3K27me3, and BAP1 protein expression in parental (P) and BAP1-WT (Ctrl) and BAP1‐KO (#1 and #2) cells. c Effect of exogenous BAP1 expression on EZH2, H3K27me3, and CAMK2D protein expression in BAP1-KO cells. V.C. indicates mock vector control.
