Fig. 1: Decreased expression of IGF2BP2 in the synovial tissues of RA patients and CIA rats.
From: IGF2BP2 regulates the inflammation of fibroblast-like synoviocytes via GSTM5 in rheumatoid arthritis
A Western blotting was used to detect IGF2BP2 protein level in synovial tissues of OA and RA patients. B IHC staining of IGF2BP2 expression in synovial tissue specimens of OA and RA patients. Scale Bar = 800 µm. C Representative photographs of morphology in the normal group and the CIA group. D, E H&E and Safranin-O staining of joints in the normal group and CIA group. Bar = 1600 µm. F Western blotting was used to detect IGF2BP2 protein levels in synovial tissues of the normal group and CIA group (n = 6 per group). G IHC staining of IGF2BP2 expression in synovial tissue specimens of the normal group and CIA group. Scale Bar = 800 µm. *P < 0.05, ***P < 0.001.
