Fig. 4
From: The chemokine monocyte chemoattractant protein-1/CCL2 is a promoter of breast cancer metastasis

Comparison of the primary tumor size, spleen weight, and lung metastases after orthotopic implantation of 4T1 breast cancer cells in WT, Ccl2-/- or Ccr2-/- mice. One hundred thousand 4T1 cells were injected into the mammary pad of mice of each genotype, and the mice were euthanized 4 weeks after tumor cell inoculation