Table 2 Immunomodulatory effects of mesenchymal stem cells against various viral infections
From: Revisiting the role of mesenchymal stem cells in tuberculosis and other infectious diseases
Viruses | Type of MSCs or component used | Effects | References |
|---|---|---|---|
Hepatitis B virus | Umbilical cord MSCs and Bone marrow MSCs | Increased bilirubin, albumin, alanine aminotransferase, aspartate aminotransferase and a model for end-stage liver disease scores. | |
Hepatitis C virus | Umbilical cord MSC-derived exosomes | Inhibition of viral replication. | [62] |
Influenza Virus | Swine bone marrow MSCs extracellular vesicles | Inhibition of viral replication and hemagglutination activity, decreased levels of proinflammatory cytokines. | [60] |
Human Immunodeficiency virus (HIV) | Umbilical cord MSCs | Increased naïve and central memory CD4+ T cells, high levels of HIV-specific IFN-γ, and IL-2 production. | [61] |
