Fig. 3: Localization of TOGARAM2 in the cochlea from a P1 wild type mouse.
From: Genetic heterogeneity in hereditary hearing loss: Potential role of kinociliary protein TOGARAM2
A Merged view of a whole mount of the mid turn of the cochlea at P1 shows the protein localization at the basal body of the kinocilium in green, the kinocilium marked with acetylated α-Tubulin in red, and the stereocilia marked with actin in blue, of outer and inner hair cells. Scale bar: 10 µm. B Representative image of stereocilia bundle using Scanning Electron Microscopy (SEM) from P4 animal indicating the base of kinocilium. C A higher magnification of the stereocilia bundles shown in A suggests that TOGARAM2 is present at the basal body of the kinocilium. Scale bar: 5 µm. D A confocal magnified view of P1 wild-type whole mount cochlea showing RAB11 (red) and TOGARAM2 (green) colocalization at the base of kinocilium. Scale bar: 5 µm.
