Fig. 1: Composition of the 3D facial image library.
From: Automated syndrome diagnosis by three-dimensional facial imaging
(a) Age distribution for syndromic; unrelated, unaffected; and unaffected relative subjects. (b) Polynomial age regression score against age plotted by group (syndromic versus unrelated, unaffected) (i) and sex (ii). 3D heatmaps showing regions of facial shape differences between sexes (iii). Shape morphs showing average facial shape changes with age by sex (iv). (c) Sample composition by self-reported sex, ethnicity, and race, as specified in the National Institutes of Health (NIH) reporting guidelines (NOT-OD-15–089). (d) Distribution of sample sizes by syndrome for all syndromes with n > 5. The dotted red line shows the cut-off for inclusion in the classification analysis at n ≥ 10).
