Fig. 3: A proposed citrus flavonoid metabolic network.

Candidate genes identified in this study are shown in their respective pathways. Metabolites and genes identified in this study are shown in bold. Flavonoids in blue, green, gray, orange and purple are flavanones, flavonols, isoflavones, flavones, and anthocyanins, respectively. The flavonoids in the box were verified by standards. UGT, UDP-glycosyltransferase; MT, S-adenosyl-L-methionine-dependent methyltransferase; OMT, O-methyltransferase family protein; CYP450, cytochrome P450; bHLH, basic helix-loop-helix (bHLH) DNA-binding superfamily protein; MYB, myb-like transcription factor family protein; 2OG-Fe(II), 2-oxoglutarate (2OG) and Fe(II)-dependent oxygenase; F3H, flavanone 3-hydroxylase