Fig. 5: Human tRNA analysis results. | Nature Communications

Fig. 5: Human tRNA analysis results.

From: A computational platform for high-throughput analysis of RNA sequences and modifications by mass spectrometry

Fig. 5

a A schematic depiction of Homo sapiens tRNA-ArgTCG, showing identified sequences that map uniquely to this isoacceptor (yellow for unmodified and orange for modified residues). Total coverage is 52%. Two different modification variants were observed at U34 (wobble position) and C40. b Aggregated coverage of the consensus tRNA sequence by oligonucleotides identified in the human tRNA dataset. Some oligonucleotide positions in long tRNAs (tRNA-Leu, tRNA-SeC, tRNA-Ser) were adjusted to fit the consensus sequence. Complementary regions in the acceptor stem (orange), D-stem (green), anticodon stem (blue) and T-stem (red) are highlighted. D D-loop, Ac anticodon loop, V variable region, T T-loop.

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