Fig. 5: Synthesis of telmisartan. | Nature Communications

Fig. 5: Synthesis of telmisartan.

From: Site-selective electrooxidation of methylarenes to aromatic acetals

Fig. 5

a Our synthetic route employing site-selective benzylic electrooxidation as a key step. b Oxidation of 75 under reported conditions for benzylic oxidation. aMe ester was recovered instead of the original tBu ester 75 because of transesterification. NHPI N-Hydroxyphthalimide, Fe(II)Pc iron(II) phthalocyanine.

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