Fig. 3: Substrate scope of ketimines 1a.
Ketimines derived from both 4-nitro-benzylamines and 2-nitro-benzylamines are employed. a1b-1j: 0.2 mmol, 2a: 0.3 mmol. Isolated yield. Dr determined by 1H NMR analysis of the crude reaction mixture. Enantioselectivity determined by chiral-stationary-phase HPLC analysis.
