Fig. 1: Cryo-EM structures of AA amyloid fibrils purified from diseased tissue.
From: AA amyloid fibrils from diseased tissue are structurally different from in vitro formed SAA fibrils
a Side views of fibril morphologies I and II: corresponding segments of the 3D maps and models, shown as ribbon diagrams. b Models of fibrils in side view. The segment shown in a is boxed. c Cross-sectional layers of fibril morphologies I and II. The 3D maps (gray surfaces) are superimposed with the models, shown as sticks. d Alignment of the fibril proteins of morphology I and II (PF-A to PF-C) as indicated in the figure. The data of morphology I is taken from a previously deposited data (PDB 6DSO: https://doi.org/10.2210/pdb6dso/pdb)50.
