Fig. 3: Exploration of substrate scopea. | Nature Communications

Fig. 3: Exploration of substrate scopea.

From: Simultaneous construction of axial and planar chirality by gold/TY-Phos-catalyzed asymmetric hydroarylation

Fig. 3

aReaction conditions: unless otherwise noted, all reactions were carried out with 0.2 mmol of 1, Au(TY5)Cl (5 mol%), NaBArF (6 mol%) in 2.0 mL DCM at 0 °C; isolated yields; the ee values were determined by chiral HPLC, >20:1 dr. bAu(TY5)Cl (10 mol%), NaBArF (12 mol%). c(Rc,Ss)-Au(TY5)Cl. CPM Cyclopropylmethyl, CBM Cyclobutylmethyl, CAM Cycloamylmethyl, AM amylmethyl, CHM Cyclohexylmethyl.

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