Fig. 1: Nanobody binding kinetics. | Nature Communications

Fig. 1: Nanobody binding kinetics.

From: A potent SARS-CoV-2 neutralising nanobody shows therapeutic efficacy in the Syrian golden hamster model of COVID-19

Fig. 1

a–d SPR sensorgrams showing binding kinetics of nanobody C5, H3, C1 and F2 for RBD Victoria (immobilised as biotinylated RBD on the chip), e–g SPR sensorgrams of competition assays between RBD and C5, H3, C1, F2 for binding to e ACE-2, f CR3022 and g H11-H4, with all ligands immobilised as Fc fusion proteins and C2Nb6 (an anti-Caspr2 nanobody) used as a negative control, h–k binding kinetics of nanobody C5, H3, C1 and F2 to Alpha RBD (l, m) C1 and F2 binding to Beta RBD (immobilised as biotinylated RBD on the chip).

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