Fig. 6: Further application of our protocol.
From: Hydroxylamine-mediated C–C amination via an aza-hock rearrangement
a Four aniline examples for catalysis/bioactive molecules precursors. b Benzyl ether/ester as substrate in the aza-Hock rearrangement. c Tertiary aniline synthesis with this protocol. d Phenol/aryl bromide synthesis with a similar strategy. Reaction conditions: alcohol (0.2 mmol), 2a (0.22 mmol) or 5 m (0.3 mmol), HFIP (hexafluoroisopropanol) (1 mL) or TFE (trifluoroethanol) (1 mL), 12 h, r.t.; Ts toluenesulfonyl, NBS N-bromosuccinimide.
