Fig. 6: Nicotine ameliorates aging-induced systemic glucose hypermetabolism.

a ROI-wise regional of 18 F-FDG uptake in 2, 6, and 16 months age C57BL/6 mice compared with 16 months age mice with nicotine administration (the white box marks the ROI. The ROI: Transverse: Brain; Sagittal: whole body, Coronal: Heart). b–d Plots show the tissues SUV of 18F-FDG. Data are means ± SEM (n = 3, biologically independent samples/group). p values were determined by one ANOVA with Tukey post hoc correction (b–d).