Fig. 5: Overlap of multi-ancestry spQRSTa loci with ECG measures. | Nature Communications

Fig. 5: Overlap of multi-ancestry spQRSTa loci with ECG measures.

From: Genetic architecture of spatial electrical biomarkers for cardiac arrhythmia and relationship with cardiovascular disease

Fig. 5

Venn diagram showing spatial QRS-T angle (spQRSTa) multi-ancestry loci where a lead variant reported for another electrocardiographic ECG measure maps within the locus boundaries. For this figure, ECG measures shown are PR interval (cardiac conduction), QRS duration (ventricular depolarization), QT and JT intervals (ventricular repolarization) and heart rate (HR). Overlap was declared if a lead variant for these ECG measures mapped to within ±500 kb or r2 > 0.1 of a lead variant at a spQRSTa locus. Some loci overlap with other ECG traits (not visualised here but presented in Supplementary Data 15). At seven spQRSTa loci, no overlap was observed with any ECG trait (blue circle bottom right).

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