Fig. 6: Increased ARID3A expression in PBC. | Nature Communications

Fig. 6: Increased ARID3A expression in PBC.

From: A regulatory variant at 19p13.3 is associated with primary biliary cholangitis risk and ARID3A expression

Fig. 6

A, B Representative immunohistochemical staining (x200; x400) and statistical analysis of ARID3A in HC (n = 10), PBC (n = 89), AIH (n = 42) and CHB (n = 20) patients. C Increased ARID3A expression in whole blood from PBC patients (HC, n = 47; PBC, n = 90). D Representative confocal staining of CD33 (in green), ARID3A (in red) and DAPI (for nuclei in blue) in the PBC liver (n = 10). E Representative confocal staining of CD11b (in green), ARID3A (in red) and DAPI (for nuclei in blue) in the PBC liver (n = 10). Data are represented as mean ± SD. P values are calculated using unpaired two-tailed Student’s t test and indicated significant if *p < 0.05, **p < 0.01, or ***p < 0.001. Scale bars, 20 μm. HC healthy control, AIH autoimmune hepatitis, CHB chronic hepatitis B.

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