Fig. 8: Dietary Clostridium butyricum rescues LrNK maturation impairment in early-Abx treated mice. | Nature Communications

Fig. 8: Dietary Clostridium butyricum rescues LrNK maturation impairment in early-Abx treated mice.

From: Early life gut microbiota sustains liver-resident natural killer cells maturation via the butyrate-IL-18 axis

Fig. 8

a Experimental scheme of the Clostridium butyricum (C. butyricum) gavage mouse model. b, c Representative FACS plots and bar graph for the expression (MFI) of maturation markers and effector molecules in LrNK cells from different groups of mice (n = 5 per group). d ELISA assay of IL-18 levels in liver tissues from different groups of mice (n = 5 per group). e, f Representative FACS plots and bar graph for the expression (MFI) of maturation markers and effector molecules in LrNK cells from different groups of mice (n = 8 per group). Dots represent data from individual mice, and error bars represent SEM per group in one experiment. Statistical analysis was performed by one-way ANOVA with Tukey’s multiple comparisons test. *P < 0.05; **P < 0.01; ***P < 0.001; ****P < 0.0001; ns, no significance. Source data are provided as a Source Data file.

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