Fig. 2: Minimal residual disease (MRD) status and outcomes.

a Longitudinal MRD assessments by NGS in peripheral blood in the Ven-Obi arm and b in the Clb-Obi arm, c landmark PFS according to MRD status in the Ven-Obi arm and d in the Clb-Obi arm, e landmark OS according to MRD status in the Ven-Obi arm and f in the Clb-Obi arm, g landmark PFS according to MRD status in the Ven-Obi arm and h in the Clb-Obi arm; ‘Not available’ indicates patients without an end of treatment MRD status, due to earlier withdrawal or missing/unevaluable samples.