Fig. 4: BLT-1 gavage generates no additive effect with REV-I. | Nature Communications

Fig. 4: BLT-1 gavage generates no additive effect with REV-I.

From: Resveratrol intervention attenuates chylomicron secretion via repressing intestinal FXR-induced expression of scavenger receptor SR-B1

Fig. 4

a Diagram shows the experimental procedures in C57BL/6J mice treated with resveratrol (HFR), or BLT-1 (B), or both (HFR + B). Body weight (b) and body weight gain (c) from week 4–6; n = 5 for the LFD group, n = 6 for the HFD group, n = 7 for the HFR group and n = 8 for the HFD + B and HFR + B groups. Epididymal white adipose tissue (d), liver weight to body weight ratio (e), fasting glucose (f), and TG levels (g) at the end of the 6th week; n = 5–8 as (b, c). h Plasma TG levels during FTT; n = 4. i, j Postprandial plasma collected 4 h after olive oil gavage was ultracentrifuged for isolating TRL. TG concentrations were then measured (i), and ApoB48 levels were assessed by Western blotting (j); n = 3. Statistical significance was evaluated by two-sided one-way ANOVA with Dunnett’s post hoc test (compared with the HFD group). *p < 0.05, **p < 0.01, ***or ###p < 0.001. For (b), *, HFD vs. HFR; ###, LFD vs. HFD. Data are presented as mean ± SD. Source data are provided as a Source Data file.

Back to article page