Fig. 2: Intrinsic suptyping of GRs and PRs. | Nature Communications

Fig. 2: Intrinsic suptyping of GRs and PRs.

From: Molecular profiling of aromatase inhibitor sensitive and resistant ER+HER2- postmenopausal breast cancers

Fig. 2

a Percent of PAM50 subtype for GRs, PRs ESR1HIGH and PRs ESR1LOW. b Change in Ki67 scores after 2wks AI vs. log2 ESR1 normalised counts from RNA-seq data marked by PAM50 subtype (LumA = blue; LumB = light blue; HER2-enriched=pink; Basal = red). c Heatmaps of median-centred log2 gene expression values supervised by GRs, PRs ESR1LOW and PRs ESR1HIGH of PAM50-subtyping genes (log2 FC from median) for POETIC data. Labelled with PAM50 subtype (LumA = blue; LumB = light blue; HER2-enriched = pink; Basal = red). Source data are provided as a Source data file.

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