Table 1 Initial studies and reaction optimization^a

^aUnless otherwise specified, the reactions were conducted with 1a (0.13 mmol), 2a (0.10 mmol), NHC (0.02 mmol), base (0.02 mmol), DQ A (0.13 mmol), 4 Å MS (150 mg) and solvent (2.0 mL) at 45 °C for 12 h.
^bIsolated yield of 3a.
^cThe er values were determined via HPLC on chiral stationary phase.
^dThe reaction uses DQ B as the oxidant.
^eThe reaction uses BQ as the oxidant.

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