Fig. 4: Important underlying microbiota of early-life microbiome age. | Nature Communications

Fig. 4: Important underlying microbiota of early-life microbiome age.

From: Delayed gut microbiota maturation in the first year of life is a hallmark of pediatric allergic disease

Fig. 4

a Top 25 most important species in predicted age determination, shaded according to the MaAsLin2 regression coefficient with predicted age, adjusting chronological age and with a random effect of the sample collection site. The size of the points represents logarithmic relative abundance. b Venn diagram of the top 25 important species in predicted age and differential within atopic disease  as compared to healthy controls. c The nine commonly identified species within one or more atopic or allergic diagnoses (1+, n = 353), two or more allergic diagnoses (2+, n = 82), and individual clinical diagnoses at 5 years, i.e., atopic dermatitis (AD, n = 212), food allergy (FA, n = 75), asthma (As, n = 103), or allergic rhinitis (AR, n = 113), at 5 years, as compared to healthy control (HC, n = 236) participants, adjusting for chronological age at the time of collection and with a random effect of the sample collection site. Data were presented as MaAslin2 coefficients ± standard error.

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