Table 1 Details of participants included in the study

From: Omicron infection following vaccination enhances a broad spectrum of immune responses dependent on infection history

 

SARS-CoV-2 naive

Previously-infected

p-value

Total number

56

38

-

Age in years (median with IQR)

41 (35.0–49.8)

48 (39.8–55.0)

0.02

Sex

 Female

33 (58.9%)

32 (84.2%)

0.01

 Male

23 (41.1%)

6 (15.8%)

Omicron subvarianta

 BA.1

39 (8 confirmed)

23 (9 confirmed)

 

 BA.2

17 (5 confirmed)

15 (6 confirmed)

-

Days from ancestral infection to 3rd mRNA vaccine dose (median with IQR)

-

544 (514–559)

-

Days from 3rd mRNA vaccine dose to omicron infection (median with IQR)

130 (88–167)

146 (95–167)

0.55

Days from 3rd mRNA vaccine dose to pre-omicron sample (median with IQR)

33 (28–49)

30 (28–36)

0.12

Days from omicron infection to post-omicron sample (median with IQR)

31 (28–34)

30 (28–36)

0.92

Site

 Liverpool

4

1

 

 Newcastle

14

9

 

 Oxford

22

7

 

 Sheffield

16

21

-

  1. aClassified by sequence data or based on a cut-off date of 20th March 2022, when >90% of SARS-CoV-2 infections in the UK were due to BA.2.
  2. IQR interquartile range. Comparison of sex between SARS-CoV-2 naive and previously-infected groups was made using Fisher’s exact test (two-sided). All other comparisons were made using Mann–Whitney U-tests (two-sided). p-values not adjusted.
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