Fig. 3: Cognitive function by years of educational attainment in PSEN1 E280A mutation carriers stratified by APOE genotype.

Mini Mental State Examination scores plotted by years of formal educational attainment in PSEN1 E280A mutation carriers stratified by a APOE e4 genotype (red: APOE e4+; black: APOE e4−) and b APOE e2 genotype (red: APOE e2−; black: APOE e2+). Plots show regression line with shaded standard error bands. MMSE = Mini Mental State Examination. Source data are provided as a Source Data file.